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BCIA Continuing Education Posts
The BioSource Faculty Explain Peer-Reviewed Science


Precision Psychopharmacology: Irritability and Rage
This case involves a 28-year-old male who presented with progressive irritability and explosive anger episodes that emerged following sequential trials of two antidepressants and subsequently a psychostimulant.
Fred Shaffer
Nov 19, 202518 min read


5-Min Science: Does Tylenol Cause Autism?
Autism is not one condition but likely represents "autisms," different biological pathways leading to outwardly similar traits.
Fred Shaffer
Sep 11, 202515 min read


5-Second Science: Nitazenes Are 50-250 Times More Potent Than Heroin
Just when you thought the opioid crisis couldn’t get worse, a new class of drugs is quietly overtaking fentanyl as the deadliest threat on the street: nitazenes.
Fred Shaffer
Jul 30, 20255 min read


5-Second Science: How Your Brain Wakes Up From Sleep
The brain follows a consistent pattern when transitioning from sleep, with specific rhythms and regions activating in a predictable sequence. These changes vary depending on the sleep stage and even predict how alert or sleepy a person feels upon waking.
Fred Shaffer
Jul 22, 20255 min read


5-Min Science: Brain Structural Differences Precede Substance Use
Children who later initiated substance use had larger brains overall, including greater whole brain volume, larger cortical surface area, and bigger subcortical structures.
Fred Shaffer
Jul 10, 202514 min read


5-Min Science: Four Distinct Types of Autism
Autism may actually be four distinct subtypes, each with its own genetic fingerprint and developmental trajectory.
Fred Shaffer
Jul 10, 20258 min read


Psychopharmacology Debates: Cannabis Associated with Cardiovascular Risk
The comprehensive analysis found that people who use cannabis are 29% more likely to experience a heart attack, 20% more likely to have a stroke, and more than twice as likely to die from heart disease compared to those who don't use cannabis.
Fred Shaffer
Jun 21, 20258 min read


How Antipsychotics Affect the EEG
Ben's case exemplifies the core insight of Dr. Swatzyna’s clinician detective model: that not all psychiatric symptoms are psychiatric in origin, and that functional abnormalities in brain activity—detectable on EEG—can signal the presence of invisible, systemic pathology.
Fred Shaffer
Jun 20, 202520 min read


How Benzodiazepines Affect the EEG
Benzodiazepines vary widely in EEG and clinical effects—Subtypes differ by half-life and receptor affinity, influencing sedation, rebound symptoms, and cortical modulation.
Fred Shaffer
Jun 16, 202514 min read


How Antidepressants Affect the EEG
Antidepressants, particularly those that are highly activating or serotonergically potent, may be the worst choice in patients with SEB, IEDs, or focal abnormalities.
Fred Shaffer
Jun 15, 202532 min read


Psychopharmacology Debates: Tylenol or NSAIDs?
Acetaminophen excels at treating mild to moderate pain when inflammation isn't a major factor.
BioSource Faculty
Jun 3, 202515 min read


5-Min Science: The Paradox of ADHD
At its core, ADHD is not about lacking attention—it's about struggling to control it.

Zachary Meehan
May 28, 202511 min read


5-Min Science: Stimulants Don't Improve Grades or Learning
Stimulant treatment does not reliably translate into better grades or sustained academic gains.
BioSource Faculty
May 6, 20257 min read


"Have We Been Thinking About ADHD All Wrong?" A Response.
EEG biomarkers offer incremental validity over behavioral observation alone.
BioSource Faculty
May 4, 202517 min read


When Should Physicians Test for FOXP1 and FOXP2 Mutations?
FOXP1 and FOXP2 mutations have been implicated in neurodevelopmental disorders and autism spectrum disorder (ASD).
BioSource Faculty
Apr 27, 202516 min read


5-Second Science: What Does Serotonin Signal?
Prospective value coding reconciles previous models of serotonin function.
BioSource Faculty
Apr 7, 20255 min read


5-Minute Science: Schizophrenia is Not a Single Disease
Schizophrenia represents multiple disorders—"schizophrenias"—each potentially with distinct biological underpinnings.
BioSource Faculty
Apr 7, 20255 min read
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