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BCIA Continuing Education Posts
The BioSource Faculty Explain Peer-Reviewed Science


Precision Psychopharmacology: Irritability and Rage
This case involves a 28-year-old male who presented with progressive irritability and explosive anger episodes that emerged following sequential trials of two antidepressants and subsequently a psychostimulant.
Fred Shaffer
1 day ago18 min read
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5-Min Science: The Role of Pacemaker Neurons in Networks Trained by Neurofeedback
Pacemaker neurons cycle between quiet and active phases on their own, creating brief bursts of action potentials that can set the tempo for larger populations.
Fred Shaffer
3 days ago11 min read
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John Anderson and John Davis Answer Your Questions About Learning Processes and Mindfulness in Neurofeedback
John Anderson and John Davis discuss learning processes and mindfulness in neurofeedback.

John Anderson and John Davis
Nov 919 min read
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John Anderson and John Davis Answer Your Neurofeedback Questions
Neurofeedback combines precise signal measurement with human learning.

John Anderson and John Davis
Nov 417 min read
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The Clinician Detective: ASD or Brain Dysregulation Due to Dysbiosis and Mold?
A global drop in amplitude suggests either a disruption in metabolic support—such as mitochondrial failure—or widespread cortical inhibition.
Fred Shaffer
Oct 1618 min read
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The Clinician Detective: How Did A FOXP4 Variant and A Sellar Cyst Complicate ASD?
The identification of the FOXP4 variant marked a turning point in the case formulation, shifting the clinical emphasis toward genomics, mitochondrial assessment, and integrative medicine.
Fred Shaffer
Oct 1323 min read
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Interpreting the Raw EEG: Alpha Squeaks
We wish clinicians—particularly those interpreting pediatric EEGs—understood that alpha squeaks are normal, age-appropriate findings that reflect an active but immature visual-cortical network.
Fred Shaffer
Oct 1211 min read
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Interpreting the Raw EEG: Triphasic Waves
Triphasic waves are among the most recognizable and clinically meaningful non-epileptiform EEG patterns encountered in patients with altered mental status.
Fred Shaffer
Oct 714 min read
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5-Min Science: Theta/Beta Ratio Neurofeedback
This study makes a valuable contribution to our understanding of the effects of neurofeedback on ADHD-related brain activity.
Fred Shaffer
Sep 253 min read
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Lynda Thompson on Neurofeedback and Biofeedback Synergy
A growing body of research and clinical innovation has underscored the need to integrate multiple therapeutic modalities like neurofeedback and biofeedback when working with clients who present with complex psychological and physiological concerns.
Fred Shaffer
Sep 143 min read
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Interpreting the Raw EEG: Frontal Intermittent Rhythmic Delta Activity (FIRDA)
Frontal intermittent rhythmic delta activity (FIRDA) is not a diagnosis—it’s a clue.
Fred Shaffer
Jul 1012 min read
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How Antipsychotics Affect the EEG
Ben's case exemplifies the core insight of Dr. Swatzyna’s clinician detective model: that not all psychiatric symptoms are psychiatric in origin, and that functional abnormalities in brain activity—detectable on EEG—can signal the presence of invisible, systemic pathology.
Fred Shaffer
Jun 2020 min read
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Interpreting the Raw EEG: Four Montages
All montages compare EEG activity between one or more pairs of electrode sites.
Fred Shaffer
Jun 2016 min read
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Interpreting the Raw EEG: Diffuse Beta Activity
The presence of diffuse beta is not inherently abnormal, but it does merit clinical consideration. It may reflect endogenous factors such as individual variability in cortical excitability, exogenous factors such as the use of CNS-active medications (e.g., benzodiazepines, barbiturates, certain anesthetics), or non-cerebral factors such as EMG contamination.
BioSource Faculty
Jun 1910 min read
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Interpreting the Raw EEG: Rhythmic Mid-Temporal Theta of Drowsiness (RMTTD)
In recordings of drowsy subjects, RMTTD often coexists with slowing of the posterior dominant rhythm and the emergence of vertex sharp waves, further supporting its link to transitional drowsiness states rather than to epilepsy or cortical dysfunction.
Fred Shaffer
Jun 198 min read
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Interpreting the Raw EEG: Slow Alpha
Not all slow alpha is a pathological sign. A subset of these slow rhythms, especially when reactive and morphologically stable, represents not a degradation of function but a subharmonic of the canonical posterior dominant rhythm (PDR), generated by the same resonant thalamocortical loop but oscillating at half the fundamental frequency.
BioSource Faculty
Jun 1914 min read
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Interpreting the Raw EEG: Fast Alpha
The most pressing clinical issue surrounding fast alpha is its frequent misclassification, particularly when spectral peaks in the 18–19 Hz range are erroneously interpreted as beta spindling, pathological fast activity, or early signs of drug effects.
Fred Shaffer
Jun 1812 min read
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Interpreting the Raw EEG: Temporal Intermittent Rhythmic Delta Activity (TIRDA)
The most common diagnostic pitfall occurs when TIRDA is misread as nonspecific temporal slowing. Many readers unfamiliar with its focal rhythmic structure mistakenly attribute it to background slowing due to prior injury or generalized dysfunction.
BioSource Faculty
Jun 1813 min read
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Interpreting the Raw EEG: Occipital Intermittent Rhythmic Delta Activity (OIRDA)
We wish clinicians knew that OIRDA is not an epileptiform discharge. It does not reflect hyperexcitability or paroxysmal depolarization, and in isolation, it is not a seizure pattern.
Fred Shaffer
Jun 1716 min read
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The Clinician Detective: Investigation Begins with Careful Observation
Before a diagnosis of a mental disorder can be made, the clinician must rule out that the symptoms are not attributable to the physiological effects of a substance or another medical condition.
Fred Shaffer
Jun 1614 min read
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